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Department of Biomedical Engineering

Directed National Science Foundation (NSF) sponsored Research Experience for Undergraduates in Cellular Bioengineering

Research

Research foci include the multi-scale analysis of CNS injury mechanics; biomaterial, tissue, and cellular engineering approaches for repair and restoration of neural functions; a biophysical analysis of traditional acupuncture; and the development of technology for electroporation that is grounded in electrohydrodynamic theory.

Education

•    Post Doctoral Training, Chemical Engineering, University of Minnesota-Twin Cities, 1998 – 2002
•    PhD & MSE, Bioengineering, University of Pennsylvania, 1991 – 1998
•    BS, Mechanical and Aerospace Engineering, Cornell University, 1987 – 1991
 

Selected Publications

1.    Drzewiecki KE, Parmar A, Gaudet ID, Branch J, Pike D, Nanda V, and Shreiber DI. Methacrylation Induces Rapid, Temperature Dependent, Reversible Self-Assembly of Type-I Collagen. Langmuir, 2014. DOI: 10.1021/la502418s.
2.    Tiryaki VM, Ayres VM, Ahmed I, and Shreiber DI. Differentiation of reactive-like astrocytes cultured on nanofibrillar and comparative culture surfaces. Nanomedicine, 2014. DOI:10.2217/nnm.14.33.
3.    Sadik MM, Yu M, Zheng M, Shreiber DI, Shan JW, Zahn ND, and Lin H. Scaling Relationship and Optimization of Double-Pulse Electroporation. Biophysical Journal, 2014. 106:801-812. DOI: 10.1016/j.bpj.2013.12.04
4.    Pan Y, Sullivan D, Shreiber DI and Pelegri AA (2013) Finite element CNS wmodeling of hite matter kinematics: use of a 3D RVE to determine material properties. Front. Bioeng. Biotechnol. 1:19. DOI: 10.3389/fbioe.2013.00019
5.    Ezra M, Bushman J, Shreiber DI, Schachner M, Kohn J. Enhanced Femoral Nerve Regeneration After Tubulization with a Tyrosine-Derived Polycarbonate Terpolymer; Effects of Protein Adsorption and Independence of Conduit Porosity. Tissue Engineering, Part A, 2014. 20(3-4): p. 518-28. DOI: 10.1089/ten.TEA.2013.0092.
6.    Masand SN, Chen J, Perron IJ, Hammerling BC, Loers G, Schachner M, and Shreiber DI, The effect of glycomimetic functionalized collagen on peripheral nerve repair. Biomaterials, 2012. 33(33): p. 8353-8362. DOI: 10.1016/j.biomaterials.2012.08.018.
7.    Gaudet ID and Shreiber D, Characterization of Methacrylated Type-I Collagen as a Dynamic, Photoactive Hydrogel. Biointerphases, 2012. 7(25): p. 1-9. DOI: 10.1007/S13758-012-0025-Y.
8.    Sundararaghavan HG, Masand SN, and Shreiber DI, Microfluidic Generation of Haptotactic Gradients through 3D Collagen Gels for Enhanced Neurite Growth. Journal of Neurotrauma, 2011. 28(11): p. 2377-2387. DOI: 10.1089/neu.2010.1606.
9.    Voyiadjis AG, Buettner HM, Shreiber DI, and Shinbrot T, Engineered In Vitro/In Silico Models To Examine Neurite Target Preference. Journal of Neurotrauma, 2011. 28(11): p. 2363-2375. DOI: 10.1089/neu.2010.1607.
10.    Masand SN, Mignone L, Zahn JD, and Shreiber DI, Nanoporous membrane-sealed microfluidic devices for improved cell viability. Biomedical Microdevices, 2011. 13(6): p. 955-961. DOI 10.1007/s10544-011-9565-z.
11.    Julias M, Buettner HM, and Shreiber DI, Varying Assay Geometry to Emulate Connective Tissue Planes in an In Vitro Model of Acupuncture Needling. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology, 2011. 294(2): p. 243-252.  DOI 10.1002/Ar.21308.