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Department of Biomedical Engineering

Research Interests

Manipulation of cellular responses for applications in biotechnology, bioengineering, immunoregulation and medicine.

Short Biography

I received my Ph.D. in immunology from the Division of Medical Sciences/Harvard Medical School and the Graduate School of Arts and Sciences at Harvard University in 1982. My thesis work focused on immunobiological regulation of antigen presentation for tumor immunity in order to gain some insight into the mechanism of tumor evasion of immune response rejection. In addition to identifying unique immunoregulatory antigen presenting cell (APC) subsets and generating novel APC immunoregulatory cell lines, this work concomitantly enabled me to understand the complexities of intercellular communication within the immune system, surface proteins which regulate this communication and ultimately the effects on animal survival. More recently, I have been associated with Rutgers University for more than 30 years and with the Department of Biomedical Engineering for more than 20 years. As a member of Dr. Yarmush’s group, my research has merged my expertise in cell biology and immunology with cellular engineering principles. One of my important research objectives is to find novel and clinically translatable engineering approaches to regulate the innate and adaptive immune responses to control inflammation and disease. 

Honors

Janet Horowitz Hecht Memorial Award in Biology, Phi Beta Kappa, Summa Cum Laude, Department Fellow, Tufts University School of Medicine, Leukemia Society of America, Special Fellow

Professional Affiliations

•    American Association of Immunologists
•    American Association for the Advancement of Science
•    New York Academy of Sciences
•    Biomedical Engineering Society

 

Education

•    Post-Doctoral Fellow, Memorial Sloan Kettering (Molecular Immunology)
•    Ph.D., Harvard University (Immunology)
•    B.S., City University of New York (CUNY), Brooklyn College (Biology)